2024 Endocrinology Grand Rounds | Endocrine Immune‐related Adverse Events (irAEs): Review of Literature and Guidelines

Duarte, CA US
May 8, 2024

Multiple endocrine immune-related adverse events (irAEs), including primary hyperthyroidism and hypothyroidism, thyroiditis, primary adrenal insufficiency, type 1 diabetes mellitus, and hypophysitis, have been reported with the use of various immune checkpoint inhibitors, and can even lead to the discontinuation of treatment. It is imperative to stay abreast of new treatment strategies and create awareness of the associated comorbid risks and early diagnosis & treatments for our cancer patients in order to effectively manage their care.   

As a cancer hospital with a large number of cancer patients receiving immunotherapy treatment, there is a need for an increased awareness irAEs so patients can be adequately diagnosed, treated and managed. Additionally, there has been an abundance of literature over the past 5 years and updated guidelines. As a result, there is a need to educate and review these guidelines with providers. Lastly, an increased awareness of endocrine irAEs will also benefit our cancer patients and families who are taking care of such patients. 

Target Audience

Faculty and Staff of department of Diabetes, Endocrinology and Metabolism.

Learning Objectives

  • Diagnose and detect endocrine immune-related adverse events (irAEs).
  • Treat endocrine iRAEs.
  • Discuss risk factors for endocrine iRAEs.
  • Identify possible new research opportunities.
  • Discuss possible barriers and biases which may impact patient care (i.e., race, ethnicity, language, gender identity/orientation, age, socioeconomic status, attitudes, feelings, or other characteristics).
Activity summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
    City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
    City of Hope designates this 2024 Endocrinology Grand Rounds | Endocrine Immune‐related Adverse Events (irAEs): Review of Literature and Guidelines for a maximum of 1.00 AMA PRA Category 1 Credit™ requirements. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  • 1.00 Attendance
Activity opens: 
05/08/2024
Activity expires: 
05/09/2024
Event starts: 
05/08/2024 - 9:00am PDT
Event ends: 
05/08/2024 - 10:00am PDT
Add to calendar: 
City of Hope
1500 E Duarte Rd
Duarte, CA 91010
United States

Virtual Meeting- Zoom

Karen Tsai, MD  Assistant Clinical Professor, Department of Diabetes, Endocrinology and Metabolism, City of Hope

Presenter: Dr. Tsai has indicated that there are no relevant financial relationships.

Planner: Pooja Manroa, MD has indicated that there are no relevant financial relationships.

This presentation and/or comments will provide a balanced, non-promotional, and evidence-based approach to all diagnostic, therapeutic and/or research related content. 

CME Committee/Reviewer no relevant financial relationships:  Daneng Li, MD

ACCREDITATION STATEMENT: City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION: City of Hope designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

The following credit type(s) are being offered for this course:

•  AMA PRA Category 1 Credit™  1.0

The following may apply AMA PRA Category 1 Credit™ for license renewal:

Registered Nurses: Nurses may report up to 1.0 credit hours toward the continuing education requirements for license renewal by their state Board of Registered Nurses (BRN). AMA PRA Category 1 Credit™ may be noted on the license renewal application in lieu of a BRN provider number.

Physician Assistants: The National Commission on Certification of Physicians Assistants states that AMA PRA Category 1 Credit™ accredited courses are acceptable for CME requirements for recertification.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
    City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
    City of Hope designates this 2024 Endocrinology Grand Rounds | Endocrine Immune‐related Adverse Events (irAEs): Review of Literature and Guidelines for a maximum of 1.00 AMA PRA Category 1 Credit™ requirements. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  • 1.00 Attendance
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