Heart failure with preserved ejection fraction (HFpEF) is a relatively new clinical description of various forms of cardiac dysfunction that may result in congestion, in the presence of normal systolic function. The mere definition of this condition and diagnostic criteria varies among society guidelines. It is, therefore, imperative to understand the pathophysiology of varying etiologies of HFpEF, in an effort to reach a consensus on how to best diagnose and treat this syndrome. 

The lack of knowledge and uniformity on how to diagnose HFpEF and how to best manage this entity is great. Recommendations have changed as new research has emerged, outlining therapies that are proven to be effective. There is need to collectively learn how to better recognize this disease and how to treat it. This requires a complete understanding of the disease itself, including its varying symptoms, contributing risk factors and comorbidities, as well as an identification of the appropriate diagnostic tools, and therapeutic approaches, in an effort to relieve the associated morbidity and mortality.