Type 1 Diabetes (T1D) is a chronic condition that requires lifelong management. Preventing it could significantly enhance the quality of life for those who would otherwise develop the disease, reducing the burden of daily insulin administration and glucose monitoring. People with T1D are at higher risk for severe complications, including cardiovascular disease, kidney damage, nerve damage, and vision problems. Preventing T1D could decrease the incidence of these complications, reducing healthcare costs and improving overall health outcomes.

There are current gaps in knowledge and practice due to advances in the field that have happened over the last few years. There are various ways researchers are looking into prevention of type 1 DM and there is a need to address their pros and cons. An updated review of the prevention of type 1 DM by various mechanisms including islet cell transplants, immunomodulation, vaccines etc. is imperative. Over the last few years, this field of research has shown enormous progress and there are FDA approved medications to delay onset of type 1 DM. Clinicians must stay abreast of the latest updates in the prevention of type 1 Diabetes mellitus.