2022 Pediatric Grand Rounds | Challenges and Strategies to Enhance CAR T Cell Efficacy, From Bedside to Bench and Back
CD19-targeted chimeric antigen receptor (CAR) T cells have shown ≥80% of remission in pediatric B-ALL with multiply relapsed/refractory disease. Unfortunately, long-term follow-up has revealed a significant proportion of patients relapse following CAR T therapy. Better understanding of mechanisms leading to resistance and relapse as well as strategies to enhance CAR T cell efficacy could lead to future development of more effective therapies.
Target Audience
City of Hope Pediatric Hematology/Oncology Physicians, Advance Practice Practitioners, City of Hope staff and research teams.
Learning Objectives
- Explain mechanisms leading to therapeutic resistance and relapse.
- Describe novel strategies to enhance CAR T cell efficacy.
- Assess pre-clinical advances in the field of CAR T cell therapy.
Virtual Meeting- Zoom
Lior Goldberg, MD, MSc Pediatric Hematology-Oncology Fellow, Children's Hospital Los Angeles
Dr. Goldberg has indicated that he has nothing to disclose.
ACCREDITATION STATEMENT: City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
CREDIT DESIGNATION: City of Hope designates this live webinar for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The following credit type(s) are being offered for this course:
• AMA PRA Category 1 Credit™ 1.0
The following may apply AMA PRA Category 1 Credit™ for license renewal:
Registered Nurses: Nurses may report up to 1.0 credit hours toward the continuing education requirements for license renewal by their state Board of Registered Nurses (BRN). AMA PRA Category 1 Credit™ may be noted on the license renewal application in lieu of a BRN provider number.
Physician Assistants: The National Commission on Certification of Physicians Assistants states that AMA PRA Category 1 Credit™ accredited courses are acceptable for CME requirements for recertification.
Available Credit
- 1.00 AMA PRA Category 1 Credit™City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
City of Hope designates this 2022 Pediatric Grand Rounds | Challenges and Strategies to Enhance CAR T Cell Efficacy, From Bedside to Bench and Back for a maximum of 1.00 AMA PRA Category 1 Credit™ requirements. Physicians should claim only the credit commensurate with the extent of their participation in the activity. - 1.00 Attendance