Rh Blood Group and the Significance of RHAG Mutation - Enduring

Molecular advances in benign hematology (Rh blood group incompatibilities or RHAG mutations) can offer novel insights that can impact care. While recognition of an incompatibility and treatment have become standard practices in newborn management, the expected course of the disease varies depending on the etiology.  Currently, several multigene panels must be sent out to diagnosis etiology of incompatibility, but advances in NGS technology allow a single test to return results that can be utilized for patient management. 

Benign hematologic conditions can impact management in pediatric oncology care.  The purpose of this lecture is to update practitioners of malignant conditions with advances in benign hematologic conditions, such as Rh blood group incompatibilities or RHAG mutations. 

Target Audience

City of Hope Pediatric Hematology/Oncology physicians, advance practice practitioners, City of Hope staff and research teams.

Learning Objectives

  • Identify hemolytic anemias caused by Rh Group incompatibilities or RHAG mutations, including RHnull phenotype.
  • Demonstrate ability to work up cause of Rh/RHAG associated hemolytic anemia and their management.
  • Explore importance of RHAG to cation exchange/ammonium metabolism and relationship to development of stomatocytes/hemolytic anemia.

Additional Information

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Activity summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
    City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
    City of Hope designates this Rh Blood Group and the Significance of RHAG Mutation - Enduring for a maximum of 1.00 AMA PRA Category 1 Credit™ requirements. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  • 1.00 Attendance
Activity opens: 
07/01/2021
Activity expires: 
07/01/2022
Internet
United States

This activity has been planned and implemented in strict compliance with the accreditation requirements, standards, and policies of the ACCME. City of Hope takes responsibility for the content, quality and scientific integrity of this CME activity.

As an accredited CME provider City of Hope requires everyone who is in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 24 months, including financial relationships of a spouse that could create a conflict of interest. Any potential conflicts relative to the previous disclosure have been resolved.

Presenter: Dr. Clarke Anderson has indicated that there is nothing to disclose.

City of Hope further encourages faculty/ authors to identify investigational products or off-label uses of products regulated by the U.S. Food and Drug Administration, at first mention and where appropriate in the content.

The information and opinions presented in this activity do not constitute medical or legal advice. Health care providers must exercise their own professional judgment in their clinical practice, and when confronted with the issues discussed herein, should not substitute this curriculum for the advice of legal counsel or application of sound ethical principles.

Rh Blood Group and the Significance of RHAG Mutation - Enduring has received no commercial support.

ACCREDITATION STATEMENT: City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION: City of Hope designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

The following credit type(s) are being offered for this course:

•  AMA PRA Category 1 Credit™  1.0

The following may apply AMA PRA Category 1 Credit™ for license renewal:

Registered Nurses: Nurses may report up to 1.0 credit hours toward the continuing education requirements for license renewal by their state Board of Registered Nurses (BRN). AMA PRA Category 1 Credit™ may be noted on the license renewal application in lieu of a BRN provider number.

Physician Assistants: The National Commission on Certification of Physicians Assistants states that AMA PRA Category 1 Credit™ accredited courses are acceptable for CME requirements for recertification.
 

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
    City of Hope is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
    City of Hope designates this Rh Blood Group and the Significance of RHAG Mutation - Enduring for a maximum of 1.00 AMA PRA Category 1 Credit™ requirements. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
  • 1.00 Attendance
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